AEFI and the pentavalent vaccine: looking for a composite picture.

Deaths following pentavalent vaccine and the revised AEFI classification.

Global Advisory Committee on Vaccine Safety review of pentavalent vaccine safety concerns in four Asian countries

Since 2008, Haemophilus influenza type b (Hib) vaccine has increasingly been introduced into Asian countries immunisation programmes. Hib vaccine has mainly been introduced as a combination pentavalent vaccine, which has replaced the traditional DTwP or DTPwP-HepB vaccines. As expected with the introduction of a new vaccine, there has been increased attention to serious adverse events following...

Revised World Health Organization (WHO)’s causality assessment of adverse events following immunization—a

The World Health Organisation (WHO) has recently revised how adverse events after immunization (AEFI) are classified. Only reactions that have previously been acknowledged in epidemiological studies to be caused by the vaccine, are classified as a vaccine-product–related-reaction. Deaths observed during post-marketing surveillance are not considered as “consistent with causal association with v...

Study of Serologic Response Rate to Pertussis after Administration of the Third Dose of Pentavalent Vaccine in Children 12 Months Old in Karaj City, Iran

Background: After substitution of Pentavalent vaccine with diphtheria, tetanus, pertussis (DTP) in the Iranian National Vaccination program with 3 Pentavalent (three times vaccination with Pentavalent vaccine at months 2, 4, and 6) in 2014 and the lack of published research in the field of immunogenicity of pertussis component of this vaccine, the efficacy of pertussis vaccine was studied 6 mon...

Supplementary report: surveillance of adverse events following immunisation among children aged < 7 years in Australia, 1 January to 30 June 2006.

This report summarises national passive surveillance data collated in the Adverse Drug Reactions Advisory Committee (ADRAC) database at 30 September 2006 for adverse events following immunisation (AEFI) reported for children aged less than 7 years who received vaccines between 1 January and 30 June 2006.1–3 It is the fi rst full reporting period for AEFI data following the introduction of a new...